Ascanio sombrero biography of williams
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Ascanio Sobrero
Italian chemist (1812–1888)
Ascanio Sobrero (12 October 1812 – 26 May 1888) was an Italian chemist, born in Casale Monferrato. He studied beneath Théophile-Jules Pelouze at the University of Turin, who had worked with the explosive ämne guncotton.
He studied medicin in Turin and Paris and then chemistry at the University of Gießen with Justus Liebig, and earned his doctorate in 1832. In 1845 he became a professor at the University of Turin.
During his research he discovered, in 1847, nitroglycerine.[1][2] He initially called it "pyroglycerine", and warned vigorously against its use in his private letters and in a journal article, stating that it was extremely dangerous and impossible to handle. In fact, he was so frightened by what he created that he kept it a secret for over a year.
Another of Pelouze's students was the young Alfred Nobel, who returned to the Nobel family's defunct armaments factory and began experimenting with the
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October 12 is Ascanio Sobrero’s birthday. Sobrero was the Italian chemist who discovered nitroglycerin.
Sobrero was a student under Théophile-Jules Pelouze. Pelouze’s laboratory specialized in studying nitrocellulose and guncotton. Sobrero synthesized a compound he called pyroglycerin by adding nitric and sulfuric acid to glycerin. Pyroglycerin was an oily, heavy and extremely explosive liquid. Its explosive nature was due to the high nitrogen content along with multiple weak oxygen and hydrogen bonds to supply fuel to its combustion. It was so explosive, Sobrero believed there were no safe means of handling the chemical and it should never be used as an explosive.
Not that this warning stopped many people. Construction and mining companies needed a more potent explosive than common black powder. Nitroglycerin, as it became to be known, was much more powerful than black powder. Many companies looked to the new chem
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A short history of nitroglycerine and nitric oxide in pharmacology and physiology
1. Nitroglycerine (NG) was discovered in 1847 by Ascanio Sobrero in Turin, following work with Theophile-Jules Pelouze. Sobrero first noted the 'violent headache' produced by minute quantities of NG on the tongue. 2. Constantin Hering, in 1849, tested NG in healthy volunteers, observing that headache was caused with 'such precision'. Hering pursued NG ('glonoine') as a homeopathic remedy for headache, believing that its use fell within the doctrine of 'like cures like'. 3. Alfred Nobel joined Pelouze in 1851 and recognized the potential of NG. He began manufacturing NG in Sweden, overcoming handling problems with his patent detonator. Nobel suffered acutely from angina and was later to refuse NG as a treatment. 4. During the mid-19th century, scientists in Britain took an interest in the newly discovered amyl nitrite, recognized as a powerful vasodilator. Lauder Brunton, the father of modern pharma