Paresh dandona bio

  • Paresh Dandona is an American physician, currently a SUNY Distinguished Professor at University at Buffalo.
  • Dr.
  • Paresh Dandona is recognized as one of the world's leading experts in the treatment of endocrine disorders, especially diabetes and obesity, and vascular.

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    General Medicine: Open Access

    ISSN - 2327-5146

    Paresh Dandona

    Division of Endocrinology and Metabolism, University at Buffalo (UB), Ambulatory Care Center, Erie County Medical Center (ECMC), Buffalo, New York

    Biography
    Dr. Paresh Dandona is ledare of Endocrinology at the State University of New York at Buffalo. He had a distinguished career in English medicine before crossing the Atlantic. A former Rhodes Scholar at Oxford, he went on to spend many years in the British medical care struktur, eventually heading the Diabetes Service at the Royal Hospital and School of Medicine in Sheffield. He came to the United States in 1991 to assume his present role and set up the Diabetes-Endocrinology Center of Western New York which he directs.

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  • paresh dandona bio

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    Paresh Dandona

    Paresh Dandona is recognized as one of the world’s leading experts in the treatment of endocrine disorders, especially diabetes and obesity, and vascular disease.

    His research on diabetes ranges from leading clinical trials for new treatments to exploring basic scientific mechanisms involved in both Type 1 and Type 2 diabetes. His team has made groundbreaking discoveries in a wide range of areas, including the following:

    • Uncovering links between obesity, diabetes and other health conditions.
    • Identifying “diabesity” as a leading cause of low testosterone in men.
    • Exploring novel treatments for diabetes, such as testosterone therapy and the use of medications designed for Type 2 diabetes, such as dapagliflozin and liraglutide, to treat patients with Type 1 diabetes.
    • Drawing new connections between inflammation and obesity and diabetes.
    • Showing that pro-inflammatory effects can contribute to development of Type 2 diabetes.
    • Investigating the an

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      Paresh Dandona MD, PhD

      Professional Summary:

      Vascular cell reactivity encompassing platelet function, endothelial function, monocyte/macrophage function and the interactions between them (adhesion molecules viz lCAM, VCAM, P-selectin, L-selectin, E-selectin, etc.). Reactive Oxygen Species (ROS) in diabetes, atherosclerosis, hypertension, aging, infection, etc. and a consequential damage to
      lipids, proteins and DNA. Regulation of aromatase, the effect of estrogen on estrogen receptor, androgen receptor and glucocortico receptor (elucidationi of pre- and post-receptor mechanisms in menopause, etc.). Venous reactivity with measurements of venous diameter and flow velocity and the effect of various drugs in NIDDM, IDDM, and IGT. Genetic regulation of aromatase and estrogen receptor. The role of nitric oxide in vascular reactivity, vis-a-vis various complications of diabetes and other factors involved with vascular reactivity. Effects of endotoxin on adhesion molecules, PAF,