Tris dhaliwal biography of abraham
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Abstract
Human immunodeficiency virus (HIV)-1 has been reported to cause tubular cell injury both in in vivo and in vitro studies. In the present study, we evaluated the role of oxidative stress in the induction of apoptosis in HIV gene expressing mouse tubular cells in in vivo (Tg26, a transgenic mouse model of HIV-associated nephropathy) and in vitro (tubular cells were transduced with pNL4-3: ΔG/P-GFP, VSV.G psueudo typed virus) studies. Although Tg26 mice showed enhanced tubular cell reactive oxygen species (ROS) generation and apoptosis, renal tissue did not display a robust antioxidant response in the form of enhanced free radical scavenger (MnSOD/catalase) expression. Tg26 mice not only showed enhanced tubular cell expression of phospho-p66ShcA but also displayed nuclear Foxo3a translocation to the cytoplasm. These findings indicated deactivation of tubular cell Foxo3A-dependent redox-sensitive stress response program (RSSRP) in Tg26 mice. In in vitro studies, NL4-3 (pNL4-3:
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Open Access
Peer-reviewed
- Mohammad H. Dezfulian,
- Danielle M. Soulliere,
- Rajdeep K. Dhaliwal,
- Madhulika Sareen,
- William L. Crosby
- Mohammad H. Dezfulian,
- Danielle M. Soulliere,
- Rajdeep K. Dhaliwal,
- Madhulika Sareen,
- William L. Crosby
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Figures
Abstract
The Arabidopsis thaliana genome encodes several families of polypeptides that are known or predicted to participate in the formation of the SCF-class of E3-ubiquitin ligase complexes. One such gene family encodes the Skp1-like class of polypeptide subunits, where 21 genes have been identified and are known to be expressed in Arabidopsis. Phylogenetic analysis based on deduced polypeptide sequence organizes the family of ASK proteins into 7 clades. The complexity of the ASK gene family, tillsammans with the close structural similarity among its members raises the prospect of significant functional redundancy among select paralogs. We have assessed the potential for
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Graduation – Class of 2025
Graduation 2025 – Friday, June 6, 2025 at Hotel Blackfoot. Calgary, Alberta. The event is held in the afternoon, and we will serve light snacks afterwards.
Graduation is an in person event! Students wear a cap and gown, and will cross the stage to receive their diploma from Principal Kaplan.
Congratulations to the VVS Class of 2024!
Congratulations to all 132 students that received their diploma from VVS in 2024!
Walter Flock – Valedictorian 2024
Every year, the VVS graduation committee recognizes a valedictorian. This is usually a student whose academic achievements set them apart from the class, but at VVS, we also consider the overall quality of the student, including the time spent at VVS. This year’s Valedictorian is an exceptional student. Walter joined VVS in 2021 and has completed his entire high school program with us. Walter has received numerous honour awards here at VVS.
Class of 2024
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